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Table 2 List of human virulence-facilitating genes

From: Genomic analyses of Burkholderia cenocepacia reveal multiple species with differential host-adaptation to plants and humans

Gene

Product

Function

Reference

cblA

cable pilus

Promotes adhesion to host epithelial cells

[55]

adhA

22 kDa-adhesin

[56]

esmR

BCESM

Burkholderia cenocepacia epidemic strain marker region

[53, 57]

amiI

cciI

cciR

opcI

kdgR

transcriptional regulator of metabolic genes

Can improve virulence

[58,59,60]

baiE

bile acid 7-alpha dehydratase

Putatively involved in a steroid degradation pathway Allows viability within host macrophage

[61,62,63,64,65]

tauX

taurine dehydrogenase

xsc

sulfoacetaldehyde acetyltransferase

telA

tellurite resistance protein

tellurite resistance

[66, 67]

terCEF

integral membrane protein

narIJHG

nitrate reductase gamma subunit

anaerobic metabolism through nitrate reduction

[68]

narL

DNA-binding response regulator

narX

Nitrate/nitrite sensor protein

lxa

low oxygen activated locus

maintains cell viability after oxygen depletion

[69]