Genome-wide association study of milk and reproductive traits in dual-purpose Xinjiang Brown cattle

BMC Genomics

Table 2 GWAS-identified significant SNPs, associated traits, and nearest candidate genes^a

Trait	SNP	Chr.	Position (bp)	MAF	Nearest Gene	Distance (kb)	P-value
Milk Traits
FP	BovineHD2400007916	24	29,095,464	0.370	CDH2	Within	1.19E-07
PY	BTB-01731924	7	75,830,763	0.140	GABRG2	Within	2.98E-10
Health Trait
SCS	BovineHD0800007286	8	24,250,348	0.484	LOC104969301	121	1.13E-09
SCS	BovineHD2200012261	22	42,292,699	0.249	FHIT	159	2.61E-08
SCS	BovineHD0500013296	5	46,291,333	0.460	DYRK2	29	1.04E-07
Reproductive Traits
AFS	BovineHD1400016327	14	58,781,799	0.378	LOC511981	69	1.32E-09
AFS	BovineHD0300035237	3	120,496,661	0.196	KIF1A	4	3.69E-08
AFS	BovineHD1600006691	16	24,235,446	0.063	EPRS	Within	6.76E-08
GL	BovineHD1400021729	14	77,464,140	0.370	LOC786994	77	5.15E-10
GL	ARS-USMARC-528	17	34,752,485	0.424	SPRY1	Within	4.99E-08
CI	BovineHD1900002007	19	7,557,250	0.278	ANKFN1	34	1.09E-10
CI	BovineHD2500003462	25	12,378,774	0.472	SHISA9	146	8.29E-08

^aSNP Single nucleotide polymorphism, MAF Minor allele frequency, Chr. Chromosome, FP Fat percentage, PY Protein yield, SCS Somatic cell score, AFS Age at first service, GL Gestation length, CI Calving interval

ISSN: 1471-2164