Skip to main content

Table 3 Summary of QTL detected by GEMMA for WW in U.S. Gelbvieh beef cattle

From: Genome-wide association and genotype by environment interactions for growth traits in U.S. Gelbvieh cattle

Chr_Mb

MAF

-log10 P-value

Supporting SNPs

Positional Candidate Genes

Lead SNP Location

Scientific Precedence [reference]; organism; trait

6_39a

0.289

18.32

107

NCAPG

Exonb

[18, 21, 30, 35,36,37,38,39]; Cattle, chicken; stature, calving ease and growth traits association, SimAngus mid-test metabolic weight association, fetal growth, carcass trait association, average daily gain and daily feed intake, muscle mass

14_25a

0.398

10.69

2

PLAG1

3’UTR

[2, 14, 18, 21, 30, 32,33,34]; Cattle; SimAngus mid-test metabolic weight association, carcass weight, stature, body weight and milk

5_60a

0.046

8.83

2

LOC527216, LOC788998

Intergenic

NA

6_36a

0.214

7.95

29

CCSER1

Intron

[14, 60]; Cattle, human; body and carcass weight association, regulator of mitosis

14_26a

0.415

7.90

11

IMPAD1, FAM110B

Intergenic

[30, 32, 34, 40]; Cattle; SimAngus mid-test metabolic weight association, carcass weight association, stature and body weight association, bone and cartilage system

6_42a

0.340

7.77

3

KCNIP4

Intron

[39, 41, 42]; Chicken, cattle, human; growth and muscle mass trait association, potassium channel activity

6_38a

0.220

7.70

9

HERC6, PPM1K

Intergenic

[49, 58, 59]; Cattle; milk, fat, and protein yield, metabolic processes, feed efficiency association

6_41a

0.238

6.46

4

LOC782905, SLIT2

Intergenic

[39, 49,50,51,52,53]; Cattle, chicken, human; milk fat and protein association, organ and muscle weight, development of central nervous system, tumor suppressor activity

6_37a

0.325

5.97

5

SNCA, GPRIN3

Intergenic

[61,62,63,64]; Human, goat, equine; neurological regulation, milk and meat associations, tendon tissue association

6_34a

0.295

5.36

4

LOC100336621, LOC104972717

Intergenic

NA

  1. a Indicates QTL was detected in EMMAX analysis
  2. b Indicates a predicted nonsynonymous mutation Ile➔Met, exon 9