Fig. 6

Analysis of enriched GO functional groups of DE genes at P0xP5 and P5xP10. Functionally grouped networks of enriched categories for DE genes between P0 and P5 (a) and between P5 and P10 (b), annotated for the cellular component, biological process, molecular function, and immune system process KEGG and GO terms. Only the most significant term in the group is labelled. GO terms are represented as nodes, and the node size represents the term enrichment significance. The edges connecting the nodes are based on the Kappa statistic (Kappa score threshold of 0.4), which measures the overlap of shared genes between terms. The right-sided hypergeometric test was used for statistical inference, and the Benjamini-Hochberg method was applied for p value correlation (p < 0.05)