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Fig. 5 | BMC Genomics

Fig. 5

From: Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

Fig. 5

Immune genes expression in tlr2+/− and tlr2−/− fish lines infected with Mm. The expression levels of il1b (a), tnfa (b), tnfb (c), irg1l (d), fosl1a (e), cebpb (f), cxcl11aa (g) and cxcl11ac (h) were determined at 4dpi by qPCR. Data (mean ± SEM) are derived from at least three biological replicates (n = 10 embryos per group) and expressed relative to their corresponding mock injection (PBS) control, which is set at 1. Statistical significance of differences was determined by two-way ANOVA with Tukey’s Multiple Comparison test as a post-hoc test. *P < 0.05, **P < 0.01, ***P < 0.001

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