LePrimAlign: local entropy-based alignment of PPI networks to predict conserved modules

BMC Genomics

Table 3 Comparison of local network alignment results and alignment quality, the average numbers of conserved edges (CE) and functionally consistent conserved edges (F-CE), after removing highly overlapping clusters

	Human-yeast network alignment				Human-fruit fly network alignment				Yeast-fruit fly network alignment
Algorithms	Num. of clusters		CE	F-CE	Num. of clusters		CE	F-CE	Num. of clusters		CE	F-CE
	Human	Yeast			Human	Fruit fly			Yeast	Fruit fly
NetworkBlast	272	289	15.493	13.768	164	158	12.408	8.663	35	34	4.278	4.056
AlignMCL	826	823	3.025	2.493	681	679	3.025	2.493	307	307	0.280	0.244
LocalAli	400	400	2.375	1.845	400	400	0.980	0.625	384	384	0.740	0.526
LePrimAlign	161	160	17.469	15.216	201	179	22.787	17.470	110	105	13.884	13.661

ISSN: 1471-2164