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Table 3 Consensus: accepting guides selected by at least n tools (except those models trained on the test data and poor performing tools)

From: Improving CRISPR guide design with consensus approaches

  Wang   Doench
Consensus level n Accepted Precision Recall NPV Accepted Precision Recall NPV
1 953 0.681 0.888 0.620 1662 0.209 0.935 0.866
2 607 0.763 0.633 0.523 1214 0.236 0.771 0.864
3 284 0.870 0.338 0.453 642 0.280 0.485 0.841
4 102 0.912 0.127 0.402 207 0.324 0.181 0.814
5 30 0.900 0.037 0.382 39 0.333 0.035 0.801
6 3 1.000 0.004 0.376 3 0.333 0.003 0.799
  1. Tools considered here: Cas-Designer, sgRNAScorer2, CHOPCHOP, CHOPCHOP-MM, PhytoCRISP-Ex and mm10db