Table 3 Consensus: accepting guides selected by at least n tools (except those models trained on the test data and poor performing tools)
From: Improving CRISPR guide design with consensus approaches
| Â | Wang | Â | Doench | |||||
|---|---|---|---|---|---|---|---|---|
Consensus level n | Accepted | Precision | Recall | NPV | Accepted | Precision | Recall | NPV |
1 | 953 | 0.681 | 0.888 | 0.620 | 1662 | 0.209 | 0.935 | 0.866 |
2 | 607 | 0.763 | 0.633 | 0.523 | 1214 | 0.236 | 0.771 | 0.864 |
3 | 284 | 0.870 | 0.338 | 0.453 | 642 | 0.280 | 0.485 | 0.841 |
4 | 102 | 0.912 | 0.127 | 0.402 | 207 | 0.324 | 0.181 | 0.814 |
5 | 30 | 0.900 | 0.037 | 0.382 | 39 | 0.333 | 0.035 | 0.801 |
6 | 3 | 1.000 | 0.004 | 0.376 | 3 | 0.333 | 0.003 | 0.799 |