Table 3 Top 5 common and tissue-specific REVIGO GO annotations in the Hyper-Variable and Hypo-Variable probe mapped gene sets of breast, cerebellum, and frontal cortex tissues
From: Human gene expression variability and its dependence on methylation and aging
Common Probe-Mapped Genes | Breast-Specific Probe-Mapped Genes | Cerebellum-Specific Probe-Mapped Genes | Frontal Cortex-Specific Probe-Mapped Genes | |
|---|---|---|---|---|
Hyper-Variable | Regulation of bone remodeling | Epithelial cell differentiation | Regulation of nervous system development | Histamine secretion |
Regulation of inflammatory response | Primary alcohol metabolism | Regulation of transmembrane transport | Regulation of cell morphogenesis | |
Response to zinc ion | Positive regulation of cellular component movement | Regulation of neuron death | Trans-synaptic signaling | |
Carboxylic acid biosynthesis | Response to corticosteroid | Negative regulation of response to external stimulus | Regulation of neurological system process | |
Regulation of ion transport | Transmembrane receptor protein tyrosine kinase signaling pathway | Response to calcium ion | Dephosphorylation | |
Hypo-Variable | Proteolysis involved in cellular protein catabolism | Golgi vesicle transport | DNA conformation change | ncRNA metabolism |
Ribonucleoprotein complex assembly | Nucleoside monophosphate metabolism | Modification-dependent macromolecule catabolism | Response to interleukin-1 | |
Regulation of cellular amino acid metabolism | Proteolysis involved in cellular protein catabolism | Response to camptothecin | Regulation of enter of bacterium into host cell | |
Innate immune response activating cell surface receptor signaling pathway | Cellular response to nitrogen starvation | Retrograde transport, endosome to Golgi | ||
Negative regulation of autophagy | Mitochondrial respiratory chain complex I assembly | Regulation of ubiquitin-protein transferase activity |