Table 4 Pearson’s Chi-squared test for Essentiality in Hyper-Variable, Hypo-Variable, and Non-Variable probe mapped gene sets
From: Human gene expression variability and its dependence on methylation and aging
Tissue | Probe Set | Total Gene Count | Essential Gene Counts | Standardized Residuals | P-Value |
|---|---|---|---|---|---|
Breast | Hyper | 1448 | 165 | 8.65 | 1.48 × 10−22 |
Hypo | 957 | 103 | 4.94 | ||
NV | 39,547 | 2095 | −9.87 | ||
Cerebellum | Hyper | 1640 | 160 | 5.88 | 4.85 × 10−10 |
Hypo | 837 | 76 | 2.69 | ||
NV | 39,485 | 2128 | −6.42 | ||
Frontal Cortex | Hyper | 1760 | 181 | 7.28 | 1.43 × 10−16 |
Hypo | 1254 | 121 | 4.15 | ||
NV | 38,948 | 2062 | −8.38 |