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Fig. 7 | BMC Genomics

Fig. 7

From: Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lung

Fig. 7

Genes that are differentially regulated in the nodal pathway related to cluster 11a. This cluster details the Epithelial sodium channel regulation in normal and cystic fibrosis airways. Among the genes downregulated in WT PA in contrast to Sphk2−/− PA are those coding for Adcy8- the adenylate cyclase 8 gene, Scnn1g- the gamma subunit of sodium channel, Plcb3, Nedd4. Furin and Edn1 were up-regulated in WT PA compared to Sphk2−/− PA. Edn1 belongs to endothelin family

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BMC Genomics

ISSN: 1471-2164

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