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Fig. 6 | BMC Genomics

Fig. 6

From: Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue transcriptomic approach

Fig. 6

Proposed mechanism leading to an increased feed intake in the LE diet. Diet fatty acids are processed by FADS1, FADS2, ELOVL5 and FADS1, leading to the production of arachidonic acid (AA). The arachidonic acid eventually lead to the production of Arachidonoyl ethanolamine (AEA), thanks to the action of NAPE-PLD. The AEA acts on CB1R, leading to an increase in feed intake. FADS1 and 2: Fatty Acid Desaturase 1 and 2, ELOVL5: Elongation Of Very Long Chain Fatty Acids Protein 5, NAPE-PLD: N-Acyl Phosphatidylethanolamine Phospholipase D, CB1R: Cannabinoid Receptor 1, AA: Arachidonic Acid, PE: Phosphatidylethanolamine, NAPE: N-arachidonoyl phosphatidylethanolamine, AEA: Arachidonoyl ethanolamine (alias Anandamide)

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BMC Genomics

ISSN: 1471-2164

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