Skip to main content

Table 2 Top 10 (based on pFDR) KEGG pathways associated with under-expressed (A) and over-expressed DEG (B) in the hypothalamus

From: Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue transcriptomic approach

Term# of genespFDR
A. Under-expressed genes in LE compared to CT
 Synaptic vesicle cycle227.36 × 10−11
 Glutamatergic synapse261.79 × 10−08
 Dopaminergic synapse262.37 × 10−07
 Axon guidance255.62 × 10−07
 Oxytocin signaling pathway272.46 × 10−06
 Circadian entrainment202.50 × 10−06
 Oocyte meiosis217.03 × 10− 06
 Protein processing in endoplasmic reticulum262.04 × 10−05
 Nicotine addiction122.04 × 10−05
 GABAergic synapse175.18 × 10− 05
B. Over-expressed genes in LE compared to CT
 Ribosome831.03 × 10−67
 Metabolic pathways1662.57 × 10−25
 Oxidative phosphorylation463.26 × 10−22
 Glycine, serine and threonine metabolism157.73 × 10−08
 Fatty acid metabolism151.81 × 10−06
 Fatty acid degradation142.52 × 10−06
 Valine, leucine and isoleucine degradation143.18 × 10−06
 PPAR signaling pathway163.65 × 10−05
 Carbon metabolism191.54 × 10−04
 Alanine, aspartate and glutamate metabolism104.70 × 10−04