Fig. 1
From: Archaic mitochondrial DNA inserts in modern day nuclear genomes
Hypotheses for NUMT introgression. Two possible scenarios for the introgression of Denisovan mitochondrial DNA (mtDNA) in modern human nuclear DNA. a The NUMT occurred in a Denisovan and introgressed together with its nuclear DNA. This path would result in a flanking region with Denisovan ancestry. b The mtDNA introgressed into a modern human, where it subsequently inserted into the nuclear DNA. mtDNA: solid colours; nuclear DNA: striped; Denisovan DNA: red; modern human DNA: blue