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Table 3 Number of differentially expressed gene (DEG) associated with immune-related KEGG pathways determined in both head kidney and liver for peptidoglycan (PGN) and poly I:C treated fish, assessed by comparison of against PBS-treated fish in each same group. Total number of DEGs of each genotype were different from the sum of values because some genes have multi-functional characteristics by KEGG pathway analysis

From: Effect of growth rate on transcriptomic responses to immune stimulation in wild-type, domesticated, and GH-transgenic coho salmon

Immune-related KEGG pathwayPGN-treated / PBS-treatedPoly I:C-treated / PBS-treated
Full nameAbbreviationHead kidneyLiverTotalDEGHead kidneyLiverTotal DEG
DTRTFWDTRTFW DTRTFWDTRTFW 
Antigen processing and presentationAPP     2 22 2  1   3
Complement and coagulation cascadesCCC 1   1 12 1      1
Cytosolic DNA-sensing pathwayCDs        0 1      1
C-type lectin receptor signaling pathwayCLRs 1    1 2 1   1  1
Chemokine signaling pathwayCs 2     12 3   1 14
Fc gamma R-mediated phagocytosisFGRP 211 1  3        0
Intestinal immune network for IgA productionIINIP        0 1      1
IL-17 signaling pathwayILs 1   2112    1  12
Leukocyte trans-endothelial migrationLTM 2 113 13        0
NOD-like receptor signaling pathwayNRs   1    1 3  12 14
Platelet activationPA     1  1        0
RIG-I-like receptor signaling pathwayRRs        0 2   1 33
Th17 cell differentiationTCD        0 1  11 13
Toll and Imd signaling pathwayTIs     1122        0
Toll-like receptor signaling pathwayTRs     2 22 2   1  2
Th1 and Th2 cell differentiationTTCD        0 1   1  1
Total 91311331021 18  48 715
Average fold change 3.03.36.910.915.85.52.89.0 12.8  7.37.9 4.216.0
  1. PBS phosphate-buffered saline, PGN peptidoglycan, Poly I:C polyinosinic-polycytidylic acid. W, non-transgenic (wild-type) coho salmon on a full satiation ration, TF GH transgenic coho salmon on a full satiation ration, TR GH transgenic coho salmon on restricted ration equal to that consumed by W, D domesticated coho salmon on a full satiation ration