Table 1 Frequency of annotation IDs that are significantly enriched in core components of pathogenic lifestyles within selected functional categories (see section “Calculation of enrichment and significance of core pathogenic functions”, Methods). Number in parentheses indicates percentage of annotations in a lifestyle, e.g., there are 10 annotations related to nucleic acids in B which represent 29.4% of the annotations of B. Numbers in bold represent abundant fuctional categories. Detailed annotations are illustrated in Additional file 2: Table S3

Amino acid metabolism

2 (5.9)

12 (15.0)

1 (6.3)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Carbohydrate metabolism

2 (5.9)

22 (27.5)

1 (6.3)

11 (36.7)

1 (14.3)

0 (0.0)

0 (0.0)

Nucleic acid related

10 (29.4)

4 (5.0)

0 (0.0)

2 (6.7)

4 (57.1)

1 (33.3)

0 (0.0)

Protease

3 (8.8)

5 (6.3)

3 (18.8)

5 (16.7)

0 (0.0)

1 (33.3)

4 (80.0)

Secondary metabolites

3 (8.8)

19 (23.8)

2 (12.5)

7 (23.3)

0 (0.0)

0 (0.0)

1 (20.0)

Signal transduction

6 (17.7)

3 (3.8)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Transporters

6 (17.7)

16 (20.0)

7 (43.8)

6 (20.0)

2 (28.6)

0 (0.0)

0 (0.0)

Chaperone

0 (0.0)

1 (1.3)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

CO₂ sensing

0 (0.0)

1 (1.3)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Energy

1 (2.9)

1 (1.3)

0 (0.0)

1 (3.3)

0 (0.0)

0 (0.0)

0 (0.0)

Light sensing and light-responsive nucleic acid functions

1 (2.9)

1 (1.3)

0 (0.0)

0 (0.0)

4 (57.1)

0 (0.0)

0 (0.0)

Oxidoreductases

0 (0.0)

2 (2.5)

1 (6.3)

1 (3.3)

0 (0.0)

0 (0.0)

0 (0.0)

Symbiosis

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

1 (33.3)

0 (0.0)

Trafficking

3 (8.8)

7 (8.8)

0 (0.0)

1 (3.3)

0 (0.0)

1 (33.3)

0 (0.0)

Translation

3 (8.8)

1 (1.3)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Unknown

1 (2.9)

4 (5.0)

2 (12.5)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Vitamin

0 (0.0)

2 (2.5)

0 (0.0)

1 (3.3)

0 (0.0)

0 (0.0)

0 (0.0)

Total annotation ID count^c

34

80

16

30

7

3

5