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Table 3 The list of genes related to GI 2 and GI 4 of subsp. pallidum. The table shows the list of proteins excluding the hypothetical proteins

From: The pan-genome of Treponema pallidum reveals differences in genome plasticity between subspecies related to venereal and non-venereal syphilis

Protein ID

GI 2 and GI 4 Coordinates

Protein Name

Functions

(MF: Molecular Function, BP: Biological Process)

WP_010881790.1

365,067–365,627

cytidylate kinase

MF: ATP binding, cytidylate kinase activity

BP: pyrimidine nucleotide metabolic process.

WP_010881791.1

365,621–366,454

adenine glycosylase

MF: catalytic activity. DNA binding.

BP: base-excision repair.

WP_010881792.1

366,459–369,881

transcription-repair coupling factor

MF: ATP binding, damaged DNA binding, hydrolase activity.

BP: regulation of transcription, DNA-template, transcription-coupled nucleotide-excision repair.

WP_010881793.1

370,034–371,125

phospho-N-acetylmuramoyl-pentapeptide- transferase

MF: phospho-N-acetylmuramoyl-pentapeptide-transferase activity, UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2, transferase activity.

BP:cell cycle, cell divisio, cell wall organization.

WP_010881797.1

373,895–374,425

FKBP-type peptidyl-prolyl cis-trans isomerase

MF: Metal ion binding, peptidyl-prolyl sis-trans isomerase activity.

BP: protein refolding

WP_010881798.1

374,639–375,925

gamma-glutamyl-phosphate reductase

MF: glutamate-5semialdehyde dehydrogenase activity.

BP: L-proline biosynthetic process.

WP_010881799.1

375,922–376,812

glutamate 5-kinase

MF: ATP-binding

BP: L-proline biosynthetic process.

WP_010881801.1

377,198–377,707

ribonuclease H

MF: Metal-ion binding, nucleic acid binding

WP_010881802.1

377,970–378,596

thymidylate kinase

MF: ATP binding, thymidylate kinase activity.

BP: dTDP biosynthetic process

WP_010881806.1

377,970–378,596

glycosyl hydrolase

MF: catalytic activity.

BP: carbohydrate metabolic process.

WP_014342391.1

382,926–383,729

lysophosphatidic acid acyltransferase

MF: transferase activity.

BP: metabolic process

WP_014505476.1

384,584–387,016

chemotaxis protein CheA

MF: ATP bindinf, phosphorelay sensor kinase activity

BP: chemotaxis.

WP_010881907.1

488,333–488,911

SMC-Scp complex subunit ScpB

BP: cell division, chromosome separation

WP_014342436.1

488,928–489,725

RsuA family pseudouridine synthase

MF: pseudouridine synthase activity, RNA binding.

WP_010881910.1

490,476–490,835

transcriptional regulator

 

WP_010881913.1

492,278–493,030

tRNA (guanine-N(7)-)-methyltransferase

MF: tRNA (guanine-N7-)-methyltransferase activity.