Fig. 1

Most of the P. falciparum genome is transcribed. a Overview of DAFT-seq data for the 3D7 time course for all of chromosome 1. Top panel: DAFT-seq coverage for plus strand. Coloured traces represent normalised coverage for each of the seven time points analysed. Middle panel: DAFT-seq coverage for minus strand. Lower panel: annotated gene models for Pf3D7v3 from GeneDB. Legend: colours of coverage traces from each of the seven time points. b Continuous coverage of DAFT-seq data allows transcript boundaries to be redefined. Orange boxes define boundaries of transcripts on the plus strand and blue boxes define boundaries of transcripts on the minus strand. Colours of coverage traces from the seven time points are the same as those shown above. c Size of 3D7 5′ UTRs based on continuous coverage of DAFT-seq data. See supplementary information for details of the computational method. d Size of 3D7 3′ UTRs based on continuous coverage of DAFT-seq data. See supplementary information for details of the computational method. e Summary statistics to describe the extent of the genome that is transcribed. At least 78% of the genome can be transcribed into mRNA