Fig. 3
Profile of specific differentially expressed genes (DEGs) and GO term enrichment analysis using the DEGs. a Volcano plot showing all profiled genes. Gray and red circles represent non-DEGs and DEGs, respectively. Statistical analysis detected DEGs between two samples using a threshold (q-value < 0.05 and a more than two-fold change in FPKM). b, c High (b) and low (c) expressed DEGs in I-MSCs compared with Mx / Md-MSCs. Venn diagram shows the number of DEGs in I-MSCs vs. Mx-MSCs (yellow circle) and I-MSCs vs. Md-MSCs (blue circle). Bar plot shows the top 10 enriched GO terms identified from co-DEGs (mid area in the Venn diagram) using statistical analysis (horizontal axis represents –log10[q-value]). Red stars indicate the GO term involved in development