Table 1 Differentially expressed (DE) genes that are strongly responsive to acute Cu exposure. Results are based on the global analysis combining all 6 controls with all 15 Cu exposed samples. Genes that were also reported to be strongly responsive to Cu exposure in a previous study by Chain et al., [53] using the 2011 draft genome are indicated by an asterisk (*)
Gene_ID | Description | blast hit with the 2011 genome annotation | log2 fold change | FDR corrected p-value | ||
|---|---|---|---|---|---|---|
edgeR | DESeq2 | edgeR | DESeq2 | |||
gene8176 | hypothetical protein DAPPUDRAFT_104167 | 104167* | −6.24 | −6.32 | 5.82E-44 | 4.45E-39 |
gene17246 | cell recognition protein caspr4 isoform 5 | 109980* | −5.05 | −5.13 | 2.07E-07 | 2.51E-07 |
gene8175 | hypothetical protein DAPPUDRAFT_225009 | 225009* | −4.35 | −4.41 | 4.49E-32 | 2.17E-28 |
gene5445 | hypothetical protein DAPPUDRAFT_313428 | 313428* | 4.98 | 4.97 | 8.54E-10 | 1.49E-17 |
gene3837 | hypothetical protein DAPPUDRAFT_222529 | 222529* | 6.92 | 6.91 | 5.40E-09 | 1.62E-20 |
gene16955 | rna polymerase ii degradation factor 1-like | 101472* | 7.25 | 7.41 | 3.66E-16 | 1.41E-12 |
gene7919 | hypothetical protein DAPPUDRAFT_324898 | ---NA--- | −5.73 | −6.11 | 3.47E-04 | 1.83E-03 |
gene7984 | metallothionein b | 290503 | 4.09 | 4.07 | 2.83E-59 | 5.07E-132 |
gene6693 | alpha-carbonic anhydrase | ---NA--- | 4.08 | 4.08 | 4.18E-03 | 3.41E-05 |
gene7509 | hypothetical protein DAPPUDRAFT_335675 | ---NA--- | 4.16 | 4.14 | 9.39E-11 | 3.37E-18 |
gene6523 | ---NA--- | ---NA--- | 4.03 | 4.30 | 1.05E-06 | 1.65E-04 |
gene3259 | hypothetical protein DAPPUDRAFT_211890 | ---NA--- | 4.17 | 4.16 | 2.33E-03 | 1.05E-05 |
gene17951 | hypothetical protein DAPPUDRAFT_313929 | ---NA--- | 4.23 | 4.23 | 1.76E-06 | 3.88E-11 |
gene8356 | hypothetical protein DAPPUDRAFT_106354 | ---NA--- | 4.44 | 4.47 | 3.05E-03 | 1.97E-05 |
gene5796 | hypothetical protein DAPPUDRAFT_229695 | ---NA--- | 4.98 | 4.99 | 1.67E-03 | 4.49E-06 |
gene9671 | hypothetical protein DAPPUDRAFT_333097 | 333097 | 5.10 | 5.10 | 1.39E-05 | 1.12E-10 |
gene12057 | hypothetical protein DAPPUDRAFT_222523 | ---NA--- | 5.39 | 5.54 | 3.92E-08 | 9.87E-07 |
gene5697 | hypothetical protein DAPPUDRAFT_337500 | 337500 | 6.75 | 7.03 | 1.06E-30 | 1.85E-13 |
gene2964 | hypothetical protein DAPPUDRAFT_244715 | ---NA--- | 7.28 | 6.70 | 1.60E-04 | 1.30E-05 |
gene1954 | vitelline membrane outer layer protein 1-like | ---NA--- | 8.68 | 8.85 | 1.07E-04 | 1.30E-07 |