Fig. 3

Quantile mapping between pairs of data sets: (a) H1 vs. ZF, (b) H2 vs. ZF, and (c) H1 vs. H2. For each mapping, a heatmap shows the number of common genes in each quantile. For across organism mappings (a and b), Row 11: genes that are expressed in zebrafish, have a high-confident orthologue in human, but are not expressed in human; Row 12: genes that are expressed in zebrafish but do not have a high-confidence orthologue in human; Column 11: genes that are expressed in human, have a high-confident orthologue in zebrafish, but are not expressed in zebrafish; Column 12: genes that are expressed in human but do not have a high-confidence orthologue in zebrafish. For H1-H2 mapping, Row/Column 11 identify the genes that are expressed in only one of the datasets. For each quantile, we also show the average TPM value shown in data value bars with a yellow background. In (d), we summarize the overlap between the top 30% of highly expressed (the 3 × 3 top-left corner of the quantile mappings in a and b) genes that are high-confidence orthologs across the two organisms for the H1 and H2 datasets