Table 1 Classification of gene clusters (ID1–54) corresponding to the dendrogram in Fig. 4

1

t1pks

1

4

–

Narbonolide/10-deoxymethynolide (pikAI – AIV), Phthiocerol/phenolphthionocerol (ppsA - E)

–

**

2

t1pks

2

–

–

Phthiocerol/phenolphthionocerol (ppsA - E)

–

–

3

t1pks

18

19

7

Azaphilone*, Lovastatin (LOVB, LOVF), Narbonolide/10-deoxymethynolide (pikAI – AIV), Phthiocerol/phenolphthionocerol (ppsA - E)

–

–

4

t1pks

22

–

–

–

–

*

5

t1pks

23

48

17

Lovastatin (LOVB, LOVF), Narbonolide/10-deoxymethynolide (pikAI – AIV), Phthiocerol/phenolphthionocerol (ppsA - E)

–

*

6

t1pks

19

43

–

Monacolin K*, Compactin, Lovastatin (LOVA, LOVB)

–

*

7

t1pks

–

–

8

Citrinin*, Narbonolide/10-deoxymethynolide (pikAI–AIV), Phthiocerol/phenolphthionocerol (ppsA-C, E)

–

*

8

t1pks

9

–

10

Byssochlamic acid*, Narbonolide/10-deoxymethynolide (pikAI–AIV), Phthiocerol/phenolphthionocerol (ppsA-C, E)

–

*

9

nrps

4

10

19

Neosartoricin*, Fengycin (fenA–E), Surfacin (srfAA-AC)

–

**

10

nrps

13

30

20

Brevianamide F (FTMA)

ABCB

**

11

nrps

7

2

–

Fengycin (fenA-E), Surfacin (srfAA-AC)

ABCC

**

12

nrps

11

23

2

Fengycin (fenA-D)

ABCC

**

13

nrps

5

22

12

Fengycin (fenA-D)

–

*

14

nrps

24

21

–

Fengycin (ppsA-D), surfacing (srfAA-AC)

ABCB

*

15

nrps

3

41

–

Fengycin (fenA–D)

–

*

16

nrps

–

–

9

Fengycin (fenB, D), Ferricrocin (SIDC, SIDD)

–

–

17

t1pks-nrps

8

40

5

NG-391*, Fengycin (fenA–E), Surfacin (surAA-AC)

ABCC

**

18

t1pks-nrps

14

27

14

Gramicidin (grsA-B), Fengycin (fenA–E), Surfacin (surAA-AC)

–

*

19

t1pks-nrps

20

13

3

Lovastatin (LOVB, LOVF), Fengycin (fenA-E), Surfactin (srfAA-AC)

ABCB

*

ID

Type of GCs

Pi

Ru

Pu

Secondary metabolic pathways detected in DNA sequence homology

ATP-binding cassettes

Identity level

20

terpene

12

24

11

Fernesyl-diphosphate (FDFT1)

–

**

21

terpene

17

12

13

Lupeol (LUP1,2,4,5), Arabidiol (PEN1), Tinucalladienol (PEN3), seco-amyrin (PEN6)

–

*

22

terpene

–

–

15

–

–

–

23

others

15

42

18

Fengycin (fenA, C, E), Surfacin (srfAA-AB)

ABCF

**

24

others

6

32

6

Kinesin (KIDFC1–3)

–

*

25

others

10

5

16

Abscisic aldehyde (AAO1–4), Fengycin (fenA, B, E), Surfactin (srfAA, AB)

ABCB

*

26

others

16

33

4

Histidinol (hisD, IE)

–

*

27

others

21

28

1

–

–

*

28

cf-putative

–

1

–

–

–

–

29

cf-putative

–

3

–

Palmitin (ZDHHC)

–

–

30

cf-putative

–

6

–

Palmitin (ZDHHC4)

–

–

31

cf-putative

–

7

–

–

–

–

32

cf-putative

–

8

–

–

–

–

33

cf-putative

–

9

–

–

–

–

34

cf-putative

–

11

–

–

–

–

35

cf-putative

–

14

–

Serine, Threonine (PP1C, 2C, 4C, 6C)

–

–

36

cf-putative

–

15

–

–

ABCG2

–

37

cf-putative

–

16

–

–

–

–

38

cf-putative

–

17

–

–

–

–

39

cf-putative

–

18

–

Mannan (ANPI, MNN9)

–

–

40

cf-putative

–

20

–

–

–

–

41

cf-putative

–

25

–

–

–

–

42

cf-putative

–

29

–

–

–

–

43

cf-putative

–

31

–

–

–

–

44

cf-putative

–

34

–

–

–

–

45

cf-putative

–

36

–

–

–

–

ID

Type of GCs

Pi

Ru

Pu

Secondary metabolic pathways detected in DNA sequence homology

ATP-binding cassettes

Identity level

46

cf-putative

–

37

–

–

–

–

47

cf-putative

–

38

–

–

–

–

48

cf-putative

–

39

–

Lovastatin (LOVB-G), Phthiocerol/Phenolphthiocerol (ppsA,C)

–

–

49

cf-putative

–

44

–

–

–

–

50

cf-putative

–

45

–

–

–

–

51

cf-putative

–

46

–

–

–

–

52

cf-putative

–

47

–

–

–

–

53

cf_fatty_acid

–

26

–

–

–

–

54

cf_fatty_acid

–

35

–

Fatty acid (FAS1,2)

–

–