Divergence of metabolites in three phylogenetically close Monascus species (M. pilosus, M. ruber, and M. purpureus) based on secondary metabolite biosynthetic gene clusters

Table 4 Percent identity of the amino acid sequence of monacolin biosynthetic genes in three Monascus species

	M. pilosus NBRC 4520		M. ruber NBRC 4483		M. purpureus NBRC 4478		Reference peptide sequence
Protein	length	(%)	length	(%)	length	(%)	length
MokA	1910	100	1910	100	1772	92.8	1910
MokB	1947	100	1947	100	1501	77.1	1947
MokC	339	100	339	100	28	8.3	339
MokD	263	100	263	100	154	58.6	263
MokE	265	100	265	100	231	87.2	265
MokF	258	100	258	100	167	64.7	258
MokG	996	99.0	977	100	322	32.3	977
MokH	487	100	487	100	42	8.6	487
MokI	174	100	174	100	107	61.5	174

Reference peptide sequence is Monascus pilosus monacolin biosynthesis gene clusters
(https://www.ncbi.nlm.nih.gov/nuccore/DQ176595.1)

ISSN: 1471-2164