Heritability and genome-wide association analyses of fasting plasma glucose in Chinese adult twins

BMC Genomics

Table 3 The top 20 genes from gene-based analysis by using VEGAS2 tool

Chr	Gene	Number of SNPs	Start position	Stop position	Gene-based test statistic	P-value	Top SNP	Top SNP P-value
2	SPATS2L^*	92	201,170,603	201,346,986	543.69	1.20E-05	rs1900706	6.05E-07
7	BRAT1	11	2,577,443	2,595,392	95.24	4.00E-05	rs77213198	5.99E-05
12	KNTC1	15	123,011,808	123,110,947	170.32	4.80E-05	rs11058797	3.12E-05
2	C2orf69	7	200,775,978	200,792,996	60.26	8.70E-05	rs3098341	5.18E-05
17	SGSH	7	78,183,078	78,194,199	67.50	1.21E-04	rs7503034	2.50E-04
1	C1orf74	3	209,955,661	209,957,890	18.31	1.22E-04	rs7550857	2.39E-03
17	CD300LF	15	72,690,446	72,709,139	88.60	1.38E-04	rs2034310	2.09E-04
2	SNRNP27	2	70,121,074	70,132,368	21.37	2.04E-04	rs1048130	1.97E-05
14	DPF3	193	73,086,003	73,360,824	533.54	2.13E-04	rs12147969	1.14E-05
17	RAB37	36	72,667,255	72,743,474	166.45	2.19E-04	rs2034310	2.09E-04
22	TSPO	4	43,547,519	43,559,248	32.32	2.77E-04	rs138915	1.98E-04
3	CLRN1	38	150,643,949	150,690,786	166.19	2.87E-04	rs12497559	3.53E-04
19	B9D2	5	41,860,321	41,870,078	55.79	3.08E-04	rs11666933	1.47E-04
2	TANK	13	161,993,465	162,092,683	73.75	3.15E-04	rs57005826	4.51E-04
11	OR4A16	3	55,110,676	55,111,663	25.49	3.41E-04	rs10896659	2.76E-04
3	GMNC	13	190,570,525	190,580,465	59.08	4.69E-04	rs75145255	1.70E-03
2	C2orf47	2	200,820,039	200,828,847	24.29	4.89E-04	rs281767	4.46E-04
21	LOC102724678	13	39,698,280	39,717,998	69.17	5.91E-04	rs62218959	2.73E-04
12	RSRC2	7	122,989,189	123,011,560	57.31	6.06E-04	rs61956121	3.59E-04
17	SLC26A11	35	78,194,199	78,227,308	207.90	6.28E-04	rs4889999	1.89E-05

Note:^* Represented the genes had already been indicated in the SNP-based analysis

ISSN: 1471-2164