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Table 3 The top 20 genes from gene-based analysis by using VEGAS2 tool

From: Heritability and genome-wide association analyses of fasting plasma glucose in Chinese adult twins

Chr Gene Number of SNPs Start position Stop position Gene-based test statistic P-value Top SNP Top SNP P-value
2 SPATS2L* 92 201,170,603 201,346,986 543.69 1.20E-05 rs1900706 6.05E-07
7 BRAT1 11 2,577,443 2,595,392 95.24 4.00E-05 rs77213198 5.99E-05
12 KNTC1 15 123,011,808 123,110,947 170.32 4.80E-05 rs11058797 3.12E-05
2 C2orf69 7 200,775,978 200,792,996 60.26 8.70E-05 rs3098341 5.18E-05
17 SGSH 7 78,183,078 78,194,199 67.50 1.21E-04 rs7503034 2.50E-04
1 C1orf74 3 209,955,661 209,957,890 18.31 1.22E-04 rs7550857 2.39E-03
17 CD300LF 15 72,690,446 72,709,139 88.60 1.38E-04 rs2034310 2.09E-04
2 SNRNP27 2 70,121,074 70,132,368 21.37 2.04E-04 rs1048130 1.97E-05
14 DPF3 193 73,086,003 73,360,824 533.54 2.13E-04 rs12147969 1.14E-05
17 RAB37 36 72,667,255 72,743,474 166.45 2.19E-04 rs2034310 2.09E-04
22 TSPO 4 43,547,519 43,559,248 32.32 2.77E-04 rs138915 1.98E-04
3 CLRN1 38 150,643,949 150,690,786 166.19 2.87E-04 rs12497559 3.53E-04
19 B9D2 5 41,860,321 41,870,078 55.79 3.08E-04 rs11666933 1.47E-04
2 TANK 13 161,993,465 162,092,683 73.75 3.15E-04 rs57005826 4.51E-04
11 OR4A16 3 55,110,676 55,111,663 25.49 3.41E-04 rs10896659 2.76E-04
3 GMNC 13 190,570,525 190,580,465 59.08 4.69E-04 rs75145255 1.70E-03
2 C2orf47 2 200,820,039 200,828,847 24.29 4.89E-04 rs281767 4.46E-04
21 LOC102724678 13 39,698,280 39,717,998 69.17 5.91E-04 rs62218959 2.73E-04
12 RSRC2 7 122,989,189 123,011,560 57.31 6.06E-04 rs61956121 3.59E-04
17 SLC26A11 35 78,194,199 78,227,308 207.90 6.28E-04 rs4889999 1.89E-05
  1. Note:* Represented the genes had already been indicated in the SNP-based analysis