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Fig. 5 | BMC Genomics

Fig. 5

From: Comparative gene expression profiling between optic nerve and spinal cord injury in Xenopus laevis reveals a core set of genes inherent in successful regeneration of vertebrate central nervous system axons

Fig. 5

KEGG pathway analyses of DESR genes expressed across multiple time points implicated the Adipocytokine signaling pathway as playing a prominent role in successful CNS axon regeneration. Black pentagons identify DESR’s. Ellipses indicate differential expression (DE; FDR < 0.05) in response to injury (up or down) in at least one tissue, during at least one time point. The Adipocytokine signaling pathway image was obtained from KEGG (Kyoto Encyclopedia of Genes and Genomes). Additional_File7_Adipocytokine_Signaling_Pathway_Gene_Expression_Data.xlsm contains an Excel spreadsheet with all 115 genes (S&L homeologs are separate entries) belonging to this pathway, together with their ΔFPKM values [log2(fold change, injury/control)], and their p and q (FDR-adjusted p) values for differential expression, at each time point, for all three tissues

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