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Table 4 Virulence genes in STEC O145:H25 strain EN1I-0044-2

From: Comparative genomic analysis of a Shiga toxin-producing Escherichia coli (STEC) O145:H25 associated with a severe pediatric case of hemolytic uremic syndrome in Davidson County, Tennessee, US

 

O145:H25

O145:H28

O157

EN1I-0044-2

CFSAN004176

CFSAN004177

RM13514

RM13516

Sakai

Virulence gene

Product

Copy (Type)

Copy (Type)

Copy (Type)

Copy (Type)

Copy (Type)

Copy (Type)

Chromosome-encoded

 bor

Bor protein

1 a

1

1

1

1

2

 eae

Intimin β type

1 (β)b

1 (β)

1 (β)

1 (γ)

1 (γ)

1 (γ)

 efa1

EHEC factor for adherence

1

2

2

+/−

1

+/−

 ehaA

Autotransporter protein

1

1

1

1

1

1

 espI

Serine protease autotransporter

(1)c

1

1

1

–

–

 gad

Serum resistance gene

2

1

1

1

–

1

 lpf cluster

Long Polar fimbriae

1

1

1

1

1

2

 sod (Cu/Zn)

Superoxide dismutase

1

1

1

2

2

2

 Stx2 genes

Shiga toxin 2

1

1

1

1

1

2 (stx1, stx2)

Plasmid-encoded

 ehxA

Enterohemolysin

1 (E)

1 (E)

1 (E)

1 (C)

1 (C)

1 (B)

 hlyA

Hemolysin A

1

–

–

1

1

1

 sfp cluster

SFP fimbria

1

1

1

–

–

-d

 sta1

Stable enterotoxin STIa

1

1

1

–

–

–

 espI

Serine protease autotransporter

1

1

1

–

–

–

  1. aThe number represents gene copy number. bCharacter or letter in parenthesis corresponds to gene type. c Number in parenthesis represents pseudogenes. d sfp cluster is absent in the O157 Sakai strain, yet it was initially described among STEC O157 strains