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Table 4 Virulence genes in STEC O145:H25 strain EN1I-0044-2

From: Comparative genomic analysis of a Shiga toxin-producing Escherichia coli (STEC) O145:H25 associated with a severe pediatric case of hemolytic uremic syndrome in Davidson County, Tennessee, US

  O145:H25 O145:H28 O157
EN1I-0044-2 CFSAN004176 CFSAN004177 RM13514 RM13516 Sakai
Virulence gene Product Copy (Type) Copy (Type) Copy (Type) Copy (Type) Copy (Type) Copy (Type)
Chromosome-encoded
bor Bor protein 1 a 1 1 1 1 2
eae Intimin β type 1 (β)b 1 (β) 1 (β) 1 (γ) 1 (γ) 1 (γ)
efa1 EHEC factor for adherence 1 2 2 +/− 1 +/−
ehaA Autotransporter protein 1 1 1 1 1 1
espI Serine protease autotransporter (1)c 1 1 1
gad Serum resistance gene 2 1 1 1 1
lpf cluster Long Polar fimbriae 1 1 1 1 1 2
sod (Cu/Zn) Superoxide dismutase 1 1 1 2 2 2
Stx2 genes Shiga toxin 2 1 1 1 1 1 2 (stx1, stx2)
Plasmid-encoded
ehxA Enterohemolysin 1 (E) 1 (E) 1 (E) 1 (C) 1 (C) 1 (B)
hlyA Hemolysin A 1 1 1 1
sfp cluster SFP fimbria 1 1 1 -d
sta1 Stable enterotoxin STIa 1 1 1
espI Serine protease autotransporter 1 1 1
  1. aThe number represents gene copy number. bCharacter or letter in parenthesis corresponds to gene type. c Number in parenthesis represents pseudogenes. d sfp cluster is absent in the O157 Sakai strain, yet it was initially described among STEC O157 strains