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Fig. 3 | BMC Genomics

Fig. 3

From: Transcriptomic analyses of Aedes aegypti cultured cells and ex vivo midguts in response to an excess or deficiency of heme: a quest for transcriptionally-regulated heme transporters

Fig. 3

Heme treatment reduces ZnMP uptake and alters gene expression in Aedes aegypti female midguts. Ae. aegypti female midguts were incubated in 0 μM or 10 μM hemin chloride for 35 h. a Background corrected ZnMP fluorescence measurements of each dissected midgut. The middle horizontal line on each treatment group represents the mean and the lines above and below represent ±1 SD. Statistical significance shown by the labels a&b. b. Background corrected pHrodoTM Green Dextran fluorescence of dissected midguts. Heme deficient and exposed midgut fluorescence not significantly distinct (p-value = 0.6316) c Log2 fold change (LogFC) vs Log10 counts per million (LogCPM) graph of genes found differentially expressed. Genes with an adjusted p-value corrected for multiple testing of < 0.00001 (false discovery rate: FDR) are shown in red. d Volcano plot of genes found differentially expressed in analysis

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BMC Genomics

ISSN: 1471-2164

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