Fig. 1
From: GMIEC: a shiny application for the identification of gene-targeted drugs for precision medicine
GMIEC framework of analysis. In the first step, the user uploads the omics datasets using a gui-interface. The main application of GMIEC, GMIEC-AN implements two methods of analysis (M1, M2). GMIEC-AN allows to analyze two (orange) or more datasets. When the user provides a file with the genomic coordinates (e.g. bed file), an annotation file (e.g. RefSeq) is also required. The only mandatory file for GMIEC is a file with the association genes – drugs (red text); users can personalize it. The output of GMIEC-AN is a tab delimited file containing the genes and drugs modules identified during the analysis. This output can be upload into GMIE-VIS to explore the results through dynamic tables. Otherwise, the user can upload the output of GMIEC-AN on GMIEC-results