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Fig. 9 | BMC Genomics

Fig. 9

From: Expression profiling of WD40 family genes including DDB1- and CUL4- associated factor (DCAF) genes in mice and human suggests important regulatory roles in testicular development and spermatogenesis

Fig. 9

Network analysis of DCAF subfamily genes. Three significant interaction networks predicted by the ingenuity pathway analysis (IPA) software (QIAGEN Inc., https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis) are presented. a Network of proteins associated with ubiquitination. b Network of proteins associated with transcription, chromatin modification, sperm maturation, sperm motility and histone modifications. c Network of proteins involved in ubiquitination, microtubule dynamics, transcription regulation, Wnt signalling pathway and spermatogonia differentiation. The shapes represent functional class of the genes product, as indicated in legend. Colored nodes are genes from the input list of DCAF genes and uncolored genes are predicted by ingenuity pathway knowledge data base as the interactors. Straight and dashed lines represent direct or indirect interactions, respectively

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BMC Genomics

ISSN: 1471-2164

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