Expression profiling of WD40 family genes including DDB1- and CUL4- associated factor (DCAF) genes in mice and human suggests important regulatory roles in testicular development and spermatogenesis

Mistry, Bhavesh V.; Alanazi, Maha; Fitwi, Hanae; Al-Harazi, Olfat; Rajab, Mohamed; Altorbag, Abdullah; Almohanna, Falah; Colak, Dilek; Assiri, Abdullah M.

doi:10.1186/s12864-020-07016-9

Table 1 The DCAF family genes and their chromosomal location in the human and mouse genomes

From: Expression profiling of WD40 family genes including DDB1- and CUL4- associated factor (DCAF) genes in mice and human suggests important regulatory roles in testicular development and spermatogenesis

Sr. No.	Human DCAF gene symbol	Human gene ID	Human chromosome location	Mouse DCAF gene symbol	Mouse gene ID	Mouse chromosome location
1	ATG16L1/WDR30	55,054	2q37.1	Atg16l1/Wdr30	77,040	1; 1 D
2	COP1/RFWD2	64,326	1q25.1-q25.2	Cop1/Rfwd2	26,374	1; 1 H1
3	CRBN	51,185	3p26.2	Crbn	58,799	6; 6 E1
4	ERCC8/CSA	1161	5q12.1	Ercc8/Csa	71,991	13; 13 D2.1
5	DCAF1/VPRBP	9730	3p21.2	Dcaf1/Vprbp	321,006	9; 9 F1
6	DCAF10/WDR32	79,269	9p13.2	Dcaf10/Wdr32	242,418	4; 4 B1
7	DCAF11/WDR23	80,344	14q12	Dcaf11/Wdr23	28,199	14 C3; 14 28.19 cM
8	DCAF12/WDR40A	25,853	9p13.3	Dcaf12/Wdr40a	68,970	4; 4 A5
9	DCAF12L1	139,170	Xq25	Dcaf12l1	245,404	X; X A4
10	DCAF12L2	340,578	Xq25	Dcaf12l2	245,403	X; X A4
11	DCAF13/WDSOF1	25,879	8q22.3	Dcaf13/Wdsof1	223,499	15; 15 B3.1
12	DCAF14/PHIP	55,023	6q14.1	Dcaf14/Phip	83,946	9; 9 E2
13	DCAF15	90,379	19p13.12	Dcaf15	212,123	8; 8 C2
14	DCAF17	80,067	2q31.1	Dcaf17	75,763	2; 2 C2
15	DCAF19/BRWD1	54,014	21q22.2	Dcaf19/Brwd1	93,871	16; 16 C4
16	DCAF2/CDT2/DTL	51,514	1q32.3	Dcaf2/Cdt2/Dtl	76,843	1; 1 H6
17	DCAF3/AMBRA1	55,626	11p11.2	Dcaf3/Ambra1	228,361	2; 2 E1
18	DCAF4/WD21A	26,094	14q24.2	Dcaf4/Wd21a	73,828	12; 12 D1
19	DCAF5/WDR22	8816	14q24.1	Dcaf5/Wdr22	320,808	12; 12 C3
20	DCAF6/IQWD1	55,827	1q24.2	Dcaf6/Iqwd1	74,106	1; 1 H2.2
21	DCAF7/WDR68	10,238	17q23.3	Dcaf7/Wdr68	71,833	11; 11 E1
22	DCAF8/WDR42A	50,717	1q23.2	Dcaf8/Wdr42a	98,193	1 H3; 1 79.54 cM
23	DCAF9/WDTC1	23,038	1p36.11	Dcaf9/Wdtc1	230,796	4; 4 D2.3
24	DDA1	79,016	19p13.11	Dda1	66,498	8; 8 B3.3
25	DDB2	1643	11p11.2	Ddb2	107,986	2; 2 E1
26	DET1	55,070	15q26.1	Det1	76,375	7; 7 D2
27	EED/ESC1	8726	11q14.2	Eed/Esc1	13,626	7 D3; 7
28	FBXW5	54,461	9q34.3	Fbxw5	30,839	2; 2 A3
29	FBXW8	26,259	12q24.22	Fbxw8	231,672	5; 5 F
30	GRWD1	83,743	19q13.33	Grwd1	101,612	7; 7 B3
31	Gβ2/GNB2	2783	7q22.1	Gβ2/Gnb2	14,693	5 G2; 5 76.54 cM
32	IFRG15/TOR1AIP2	163,590	1q25.2	Ifrg15/Tor1aip2	240,832	1; 1 G3
33	KATNB1	10,300	16q21	Katnb1	74,187	8; 8 C5
34	mβTrCP/BTRC	8945	10q24.32	Mβtrcp/Btrc	12,234	19; 19 C3
35	NLE1	54,475	17q12	Nle1	217,011	11; 11 C
36	NUP43	348,995	6q25.1	Nup43	69,912	10; 10 A1
37	PAFAH1B1/LIS1	5048	17p13.3	Pafah1b1/Lis1	18,472	11 B5; 11 45.76 cM
38	PWP1	11,137	12q23.3	Pwp1	103,136	10; 10 C1
39	RBBP4	5928	1p35.1	Rbbp4	19,646	4; 4 D2.2
40	RBBP5	5929	1q32.1	Rbbp5	213,464	1; 1 E4
41	RBBP7	5931	Xp22.2	Rbbp7	245,688	X; X F4
42	SMU1	55,234	9p21.1	Smu1	74,255	4; 4 A5
43	TLE1	7088	9q21.32	Tle1	21,885	4; 4 C3
44	TLE2	7089	19p13.3	Tle2	21,886	10; 10 C1
45	TLE3	7090	15q23	Tle3	21,887	9; 9 B
46	TRPC4AP	26,133	20q11.22	Trpc4ap	56,407	2 H1; 2 77.26 cM
47	WDR12	55,759	2q33.2	Wdr12	57,750	1; 1 C2
48	WDR26	80,232	1q42.11-q42.12	Wdr26	226,757	1; 1 H4
49	WDR39/CIAO1	9391	2q11.2	Wdr39/Ciao1	26,371	2 F1; 2 61.86 cM
50	WDR5	11,091	9q34.2	Wdr5	140,858	2; 2 A3
51	WDR51B/POC1B	282,809	12q21.33	Wdr51b/Poc1b	382,406	10; 10 C3-D1
52	WDR53	348,793	3q29	Wdr53	68,980	16; 16 B2
53	WDR57/SNRNP40	9410	1p35.2	Wdr57/Snrnp40	66,585	4; 4 D2.2
54	WDR59	79,726	16q23.1	Wdr59	319,481	8; 8 E1
55	WDR5B	54,554	3q21.1	Wdr5b	69,544	16; 16 B3
56	WDR61	80,349	15q25.1	Wdr61	66,317	9; 9 A5.3
57	WDR76	79,968	15q15.3	Wdr76	241,627	2; 2 E5
58	WDR82	80,335	3p21.2	Wdr82	77,305	9; 9 F1
59	WSB1	26,118	17q11.1	Wsb1	78,889	11; 11 B5
60	WSB2	55,884	12q24.23	Wsb2	59,043	5; 5 F
61	DCAF16	54,876	4p15.31	Absent in mouse	–	–
62	DCAF4L1	285,429	4p13	Absent in mouse	–	–
63	DCAF4L2	138,009	8q21.3	Absent in mouse	–	–
64	DCAF8L1	139,425	Xp21.3	Absent in mouse	–	–
65	DCAF8L2	347,442	Xp21.3	Absent in mouse	–	–

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