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Table 1 Representation of wzb-wzd synteny EPS cluster a of L. rhamnosus LRHMDP2, LRHMDP3 in L. rhamnosus 699_LRHA, 708_LRHA, Lactobacillus spp. (L. rhamnosus) HMSC077C11 and L. rhamnosus BPL5, BPL15

From: Intra-species variation within Lactobacillus rhamnosus correlates to beneficial or harmful outcomes: lessons from the oral cavity

ORF

Gene Description

HMSC077C11

699_LRHA

708_LRHA

LRHMDP2

LRHMDP3

BPL15

BPL5

Number of L. rhamnosus strains with the protein ortholog

wzb

tyrosine protein phosphatase

WP_015765006.1

WP_061713774.1

166

wzr

Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily F2

WP_005715254.1

WP_061713383.1

166

welE

sugar transferase

WP_070586506.1

WP_049168896.1

WP_005715255.1

WP_061713382.1

152

hypothetical

hypothetical protein

WP_005715256.1

WP_061713381.1

66

lipopolysaccharide biosynthesis protein b

lipopolysaccharide biosynthesis protein

WP_005715258.1

P c

WP_061713380.1

7

wchA b

glycosyltransferase family 2 protein

WP_005715259.1

7

Polysaccharide transferase protein b

polysaccharide pyruvyl transferase family protein

WP_005715260.1

P c

WP_005715260.1

WP_061713379.1

7

welL

glycosyltransferase family 2 protein

WP_005715262.1

WP_061713378.1

48

Hypothetical b

hypothetical protein

P c

P c

P c

WP_005715263.1

P c

P c

P c

7

Polymerase b

oligosaccharide repeat unit polymerase

WP_005717894.1

P c

WP_005715264.1

WP_005717894.1

P c

P c

7

hypothetical protein

hypothetical protein

WP_050562870.1

WP_049175362.1

WP_049168568.1

WP_050562870.1

WP_081014187.1

WP_050562870.1

34

WelJ/WciB

DUF4422 domain-containing protein

WP_005715265.1

WP_061713377.1

84

glf

UDP-galactopyranose mutase

WP_005715266.1

89

wze

polysaccharide biosynthesis tyrosine autokinase (CpsD/CapB family tyrosine-protein kinase)

WP_005715267.1

WP_061713376.1

162

wzd

Tyrosine-protein kinase modulator EpsC

WP_005715268.1

WP_061713375.1

165

  1. a: wzb-wzd synteny EPS cluster identified using the protein othology tool ProteinOrtho,
  2. b: Genes specifically conserved in L. rhamnosus LRHMDP2, LRHMDP3, L. rhamnosus 699_LRHA, 708_LRHA, Lactobacillus spp. HMSC077C11 and L. rhamnosus BPL5, BPL15 (Bold)
  3. c: The genes marked as “P” were also found to be present but had to be identified using tblastn alignments against genomes and hence “WP_” identifiers from NCBI are not available (Bold)