Table 4 List of top 20 R. conorii genes differentially expressed during the infection of human microvascular endothelial cells, in vitro
Gene ID | Product | Gene Length (bp) | TPM | Log2 Change | Homologous to | ||||
|---|---|---|---|---|---|---|---|---|---|
AAE2 + Rc | HMEC + Rc | Product | Organism | E-value | Identity (%) | ||||
RC0257 | Hypothetical protein | 135 | 8 | 743 | 6.52 | Autotransporter outer membrane beta-barrel domain-containing protein | Citrobacter farmeri | 7e-04 | 15% |
peg.1116 | Hypothetical protein | 114 | 10 | 263 | 4.78 | Sugar (and other) transporter family protein | R. hoogstraalii | 2e-14 | 92 |
peg.0736 | Hypothetical protein | 186 | 6 | 130 | 4.47 | Spore Coat Protein U domain protein | R. hoogstraalii | 2e-21 | 89 |
peg.0341 | Hypothetical protein | 129 | 25 | 522 | 4.36 | ATP-binding cassette domain-containing protein | R. fournieri | 3e-13 | 92 |
RC0682 | LSU ribosomal protein L36p, zinc-independent (RpmJ) | 126 | 26 | 494 | 4.25 | Â | Â | Â | Â |
RC0395 | Hypothetical protein | 297 | 11 | 187 | 4.09 | – | – | – | – |
RC1180 | Hypothetical protein | 138 | 24 | 302 | 3.67 | MFS transporter | Chrysiogenales bacterium | 7e-06 | 39 |
RC1181 | Hypothetical protein | 267 | 45 | 526 | 3.55 | Putative MFS transporter | Aeromonas salmonicida | 6e-22 | 34 |
peg.0129 | Hypothetical protein | 120 | 27 | 311 | 3.51 | ATP synthase A chain | R. slovaca | 0.009 | 100 |
peg.1274 | Hypothetical protein | 114 | 57 | 546 | 3.25 | – | – | – | – |
RC0196 | Hypothetical protein | 174 | 13 | 114 | 3.18 | Nucleoside triphosphate pyrophosphohydrolase | M. smegmatis | 5e-17 | 45 |
RC1177 | Hypothetical protein | 240 | 32 | 265 | 3.06 | MFS transporter | R. felis | 5e-30 | 84 |
RC1123 | Hypothetical protein | 156 | 7 | 56 | 3.01 | Myotubularin-related protein 10-B | Cephus cinctus | 4e-13 | 27 |
peg.0810 | Hypothetical protein | 114 | 29 | 218 | 2.93 | Type II toxin-antitoxin system RelB/DinJ family antitoxin | Psychrobacter | 4e-10 | 30 |
peg.1527 | Hypothetical protein | 129 | 42 | 307 | 2.86 | – | – | – | – |
RC0824 | Hypothetical protein | 282 | 71 | 503 | 2.83 | BrnT family toxin | Limnohabitans | 2e-19 | 52 |
RC0149 | Acetate kinase (EC 2.7.2.1) | 252 | 9 | 61 | 2.82 | Â | Â | Â | Â |
RC0530 | Rickettsial conserved | 207 | 68 | 477 | 2.8 | Holliday junction ATP-dependent DNA helicase RuvA | R. fournieri | 1e-13 | 97 |
RC0364 | Hypothetical protein | 186 | 176 | 1109 | 2.66 | Palindromic element RPE1 domain-containing protein | R. hoogstraalii | 1e-20 | 80 |
RC0033 | PqqC-like protein | 303 | 75 | 471 | 2.64 | Pyrroloquinoline quinone biosynthesis protein PqqC | R. japonica | 6e-34 | 97 |