Fig. 2

Open chromatin localization and differential accessibility. a Distribution of cattle and pig consensus open chromatin relative to genomic features. Because peaks often span multiple features, peaks were categorized based on 1 bp overlap with features in the following order: first as TSS (±50 bp), then as promoter (2 kb upstream of TSS), transcription termination site (TTS) (±50 bp), 5′ untranslated region (UTR), 3′ UTR, coding sequence (CDS), intronic, and if no features were overlapped, peaks were considered intergenic. b Distribution of consensus peak activity, ranging from tissue-specific (accessible in only one tissue) to ubiquitous (accessible in all sampled tissues). Consensus peaks that were accessible in a single tissue were further broken down by tissue. c Distribution of consensus peak activity for regions containing CTCF motifs