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Table 3 Standard diversity indices and global-selection at individual genes and at sub-region-level

From: Genetic diversity, evolution and selection in the major histocompatibility complex DRB and DQB loci in the family Equidae

Locus/sub-region Length (bp) N VNP PIP Z-test
     p-value dN-dS
DQB1 locus 269 17 99 68 0.033 1.856
DQB2 locus 269 19 92 46 0.062 1.550
DQB3 locus 269 14 13 3 1.000 −0.610
DQB2-like sequence 269 9 32 24 1.000 −0.156
DQB sub-region 269 59 141 104 0.042 1.747
DRB1 locus 260 16 93 67 1.000 −0.303
DRB2 locus 260 20 63 37 0.157 1.012
DRB3 locus 260 15 40 11 1.000 −0.204
DRB sub-region 260 52 114 84 0.375 0.318
  1. N numbers of sequences, VNP variable nucleotide positions, PIP parsimony informative positions. Z-test p-value: probability of rejecting the null hypothesis of strict-neutrality (dN = dS) in favor of dN > dS. Significant p-values are in bold