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Table 2 Overview on post-translational modifications (without oxidations) of Acb proteins of Actinoplanes sp. SE50/110 during growth

From: The expression of the acarbose biosynthesis gene cluster in Actinoplanes sp. SE50/110 is dependent on the growth phase

Protein

Annotated function

Modification(s)

Time Point(s)

AcbZ

acarbose-resistant alpha-amylase

Gln → pyro-Glu

T1; T3; T4; T6

AcbW

ABC-type transporter; ATPase

Gln → pyro-Glu

T4; T6

AcbU

1-epi-valienol-7-phosphate 1-kinase

Gln → pyro-Glu

T3

AcbR

1-epi-valienol-1,7-bisphosphate-1-adenylyltransferase

Gln → pyro-Glu

T4

AcbQ

acarbose 4-alpha-glucanotransferase; amlyomaltase

Acetylation

Gln → pyro-Glu

T3

T5

AcbO

2-epi-5-epi-valiolone-7-phosphate 2-epimerase

Gln → pyro-Glu

T3

AcbE

acarbose-resistant alpha-amylase

Gln → pyro-Glu

T3; T4

AcbD

acarviose transferase

Gln → pyro-Glu

T2; T5; T7