Fig. 4

Estimation of execution time and memory usage of NGS-Integrator ‘Calculator’ and ‘Integrator’. a Execution time (left panel) and memory usage (right panel) of NGS-Integrator ‘Calculator’ was assessed from different sizes of chromosomes (chromosome 1, 10, 17, and 19) with multiple scale bins (1000 bp, 500 bp, 100 bp, 50 bp, 10 bp, and 5 bp). ‘Calculator’ was tested as default setting (window size: 10000 bp; number to replace zero: 0.1). b Execution time and memory usage of NGS-Integrator ‘Integrator’ estimated from cMBFs of three replicates in each chromosome size. The performance analysis was accomplished using 2 Hexa core Intel Xeon CPU E5–2620 running at 2.40GHz with 32 KB of L1 instruction cache, 32 kb of L1 data cache, 256 kb of L2, and 15,360 kb of L3 cache. The Linux system was equipped with 48GB of RAM memory and operating system was 3.13.0–48 generic Ubuntu