Table 1 Overrepresented GO-Slim terms among DE genes
Genes in reference list | Genes in analyzed list | Fold enrichment | Raw p-value | FDR | |
|---|---|---|---|---|---|
GO-Slim Biological Process | |||||
Angiogenesis (GO:0001525) | 30 | 8 | 8.28 | 1.84E-05 | 0.0025 |
Extracellular matrix organization (GO:0030198) | 69 | 15 | 6.75 | 4.45E-08 | 2.66E-05 |
Cell morphogenesis (GO:0000902) | 60 | 9 | 4.66 | 2.82E-04 | 0.023 |
Regulation of cell migration (GO:0030334) | 70 | 9 | 3.99 | 7.79E-04 | 0.047 |
Regulation of cAMP-mediated signaling (GO:0043949) | 118 | 12 | 3.16 | 7.76E-04 | 0.048 |
Transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169) | 197 | 18 | 2.84 | 1.48E-04 | 0.013 |
Cell adhesion (GO:0007155) | 373 | 34 | 2.83 | 2.15E-07 | 6.43E-05 |
Actin cytoskeletal organization (GO:0030036) | 179 | 16 | 2.78 | 4.26E-04 | 0.027 |
GO-Slim Molecular Function | |||||
Extracellular matrix structural constituent (GO:0005201) | 53 | 12 | 7.03 | 6.82E-07 | 0.0002 |
Metalloendopeptidase activity (GO:0004222) | 42 | 7 | 5.18 | 7.66E-04 | 0.043 |
Actin binding (GO:0003779) | 148 | 20 | 4.20 | 3.11E-07 | 0.0002 |
GO-Slim Cellular Component | |||||
Collagen trimer (GO:0005581) | 10 | 4 | 12.42 | 7.32E-04 | 0.015 |
Apical junction complex (GO:0043296) | 11 | 4 | 11.29 | 9.73E-04 | 0.018 |
Collagen-containing extracellular matrix (GO:0062023) | 33 | 10 | 9.41 | 6.16E-07 | 6.91E-05 |
Dendritic spine (GO:0043197) | 27 | 5 | 5.75 | 2.91E-03 | 0.048 |
Supramolecular fiber (GO:0099512) | 54 | 9 | 5.18 | 1.39E-04 | 0.0046 |
Actin cytoskeleton (GO:0015629) | 225 | 25 | 3.45 | 3.28E-07 | 4.90E-05 |
Receptor complex (GO:0043235) | 177 | 16 | 2.81 | 3.80E-04 | 0.0085 |
Integral component of plasma membrane (GO:0005887) | 733 | 51 | 2.16 | 8.91E-07 | 7.99E-05 |