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Table 3 Case 1 p-value rankings for HDR1 Animal compared to Control 1 Animal

From: Detection of CRISPR-mediated genome modifications through altered methylation patterns of CpG islands

      Degree of Experimental Methylation Level Higher Than Control
Chromosome CpG Island Start Location CpG Island End Location p-value CpG Count 1–20% Proportion 1–20% 21–40% 41–60% 61–80% 81–100%
15 11,035,894 11,038,084 3.852E-48 91 0.034 3 9 26 45 6
5 141,975,051 141,975,377 6.732E-12 23 0.043 1 10 10 2 0
15 89,523,499 89,524,359 1.555E-09 62 0.388 19 21 8 1 0
1 126,092,971 126,093,200 2.973E-09 16 0.125 2 5 8 1 0
7 45,098,344 45,098,676 2.978E-09 15 0.000 0 0 4 7 3
10 128,262,409 128,262,692 2.055E-08 12 0.083 1 10 1 0 0
8 116,827,244 116,827,574 2.268E-08 13 0.077 1 1 9 2 0
4 22,057,643 22,057,924 6.841E-08 11 0.000 0 10 1 0 0
15 38,118,394 38,118,655 7.345E-08 16 0.250 4 11 1 0 0
19 38,914,796 38,915,109 9.360E-08 12 0.083 1 7 4 0 0
  1. The p-value represents the upper-tail p-value for the hypothesis test of higher methylation in the experimental mouse than the control mouse. The CG count includes the total number of CGs in the CpG island. The proportion and category counts only refer to the number of CGs where the experimental CG methylation level is higher than the control CG methylation level