Fig. 5

Network visualization of the effect of dehydration/rehydration on cat ovarian cortex. a Enrichment map displaying enriched gene-sets based on differentially expressed genes between dehydrated for 10 min (D10) and fresh (F) tissue. Blue node color represents enrichment in fresh tissue (i.e., down-regulation after 10 min dehydration), whereas green color represents enrichment in both dehydrated and fresh tissue (i.e., both up-regulation and down-regulation after 10 min dehydration). Borders are colored according to the enrichment p-value (EASE score). Clusters of functionally related gene-sets were identified using DAVID tool, manually circled and assigned a label. Additional file 6 contains the web session of the network for interactive view. b STRING network for 134 proteins retrieved from the list of differentially expressed genes in comparison pair D10 vs. F. Full gene list of the pair D10 vs. F resulted in 71 functional associations between 41 of the proteins; proteins with less than three associations to other proteins in the network were removed. Each cluster was analyzed for functional enrichment within STRING app. Nodes are shaped according to the comparison pair source of differentially expressed genes. Nodes are colored according to the gene abundance (fold change) in dehydrated/rehydrated compared to fresh cortex; borders are colored according to the adjusted p-value of the differentially expressed gene. The confidence cutoff was set to 0.4, the confidence score of each interaction is mapped to the edge thickness. Additional file 7 contains the web session of the network for interactive view