Fig. 6
From: Meta-Apo improves accuracy of 16S-amplicon-based prediction of microbiome function
Cross-platform comparison of healthy and gingivitis oral microbiomes based on non-calibrated and calibrated functional profiles. a Functional patterns derived from the amplicon and WGS approaches are distinct, which suggests cross-platform comparison can be a significant challenge under such circumstances. b Comparing the effect size of the sampling factors by Adonis test. c Meta-Apo aligns the predicted functional profiles of amplicon samples to those of the WGS samples. d Healthy status classification of the original and the Meta-Apo-calibrated amplicon samples by MSE-based classification from WGS samples. Distances for Adonis test and PCoA were calculated using Bray-Curtis metrics