Fig. 1

Circular representation of Ehrlichia sp. HF genome. From outside to inside, the first circle represents predicted protein coding sequences (ORFs) on the plus and minus strands, respectively. The second circle represent RNA genes, including tRNAs (black), rRNAs (red), tmRNAs (blue), and ncRNAs (orange). The third circle represents GC skew values [(G-C)/(G+C)] with a windows size of 500 bp and a step size of 250 bp. Colors indicate the functional role categories of ORFs - black: hypothetical proteins or proteins with unknown functions; gold: amino acid and protein biosynthesis; sky blue: purines, pyrimidines, nucleosides, and nucleotides; cyan: fatty acid and phospholipid metabolism; light blue: biosynthesis of cofactors, prosthetic groups, and carriers; aquamarine: central intermediary metabolism; royal blue: energy metabolism; pink: transport and binding proteins; dark orange: DNA metabolism and transcription; pale green: protein fate; tomato: regulatory functions and signal transduction; peach puff: cell envelope; pink: cellular processes; maroon: mobile and extrachromosomal element functions