Fig. 6

ClueGO network visualization of enriched GO terms and DEGs in brain transcriptomes from S. salar, D. labrax and D. rerio. Directionally regulated DEGs in proactive phenotypes from each species were analysed expression-pattern-wisely. Enriched/Depleted GOs are identified by a two-sided hypergeometric test with adjusted p-values (Benjamini-Hochberg) < 0.05. In each sub-panel: a) proactive-up and c) proactive-down regulated DEGs and associated GO networks from D. rerio, S. salar and D. labrax are shown in red, green and blue respectively. The colour gradient shows the gene proportion of each cluster associated with the term. GO terms with < 60% of genes from all three clusters are defined as “shared terms” and represented in grey. b) proactive-up and d) proactive-down regulated functional groups for shared GO terms across all three species. The name of each group is named using the most significant term in the group. Group sections represent the number of the terms included in each group. P-values: “**” < 0.001, 0.001 < = “*” < 0.05