Fig. 3

Experimental validation of candidate reference genes in exosomes of patients with ovarian cancer and healthy control individuals. Expression levels (Ct values) of candidate reference genes in exosomes of ovarian cancer patients (red bars) and healthy control individuals (blue bars) relative to 18S rRNA (a). Expression stability of the candidate reference genes in serum exosomes of ovarian cancer patients (b) and healthy control individuals (c) as measured by the “CV” indicator. Expression stability of the candidate reference genes in serum exosomes of ovarian cancer patients (d) and healthy control individuals (e) as measured by the “M” indicator