Fig. 5
![Fig. 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12864-020-07326-y/MediaObjects/12864_2020_7326_Fig5_HTML.png)
The F. hepatica life cycle stages have distinct secretome profiles. a Graphical representation of the top 50 proteins secreted by the immature flukes representing 87% of the total protein secreted (based on emPAI values of three biological replicates), highlight that the immature fluke secretome is predominantly comprised of cathepsin peptidases and cathepsin peptidase inhibitors. b Graphical representation of the composition of the F. hepatica stage-specific secretomes, based on the emPAI abundance. Relative abundance is shown by a blue to red scale, depicting low to high levels of abundance, respectively. c Venn diagram representing the comparative analyses of proteins secreted by newly excysted juveniles 24 h post excystment (NEJ 24 h), the immature parasites (Juv21dpi) and the adult parasites. The protein count is based on a cut-off of at least 2 unique peptides