Table 3 Over-representation of known biosynthetic gene clusters present in 5 neutrotolerant acidophilic Streptomyces and their comparison with 14 non-acidophilic Streptomyces species used in this study. Known BGC that were present in S. yeochonensis CN732 and at least in two or more neutrotolerant genomes were considered
Cluster type | Most similar known cluster | MIBiG BGC-ID | Distribution (%) | |
|---|---|---|---|---|
Acidophilic | Non-acidophilic | |||
Siderophore | Desferrioxamine B | BGC0000941_c1 | 80 | 28.6 |
T2PKS | Spore pigment | BGC0000271_c1 | 100 | 71.4 |
Melanin | Istamycin | BGC0000700_c1 | 100 | 21.4 |
T1PKS-NRPS | Meilingmycin | BGC0000093_c1 | 80 | 28.6 |
Terpene | 2-methylisoborneol | BGC0000658_c1 | 40 | 35.7 |
T3PKS | Alkylresorcinol | BGC0000282_c1 | 80 | 14.3 |
Terpene | Hopene | BGC0000663_c1 | 100 | 92.9 |