Table 2 Summary of datasets used to compare the prediction tools
Name | Used | Origin | Control data | N (Positive / Control; %) |
|---|---|---|---|---|
Ensembl data | Identification of BPs among background noise | 3’ss supported by the transcripts described in Ensembl database | Any AG dinucleotides in the gene sequence | 114,868,082 (264,787 / 114,603,295; 0.23%) |
RNA-seq data | Correlation between expression of 3’ss and BP predictions | Alternative 3’ss observed in RNA-seq experiments | Random selection of 3’ss with MES score > 0 | 103,972 (51,986 / 51,986; 50%) |
Variants collection | Detection of BP alteration by a variant | Variants occurring in the BP area (−44; −18) with in vitro RNA studies | Variants without impact on splicing | 120 (38 / 82; 31.7%) |