Table 3 Performance of tools derived from contingency table with Ensembl dataset (n = 114,868,082)
SVM-BPfinder | BPP | Branchpointer | LaBranchoR | RNABPS | |
|---|---|---|---|---|---|
Cutoff | 0.706 | 5.384 | – | 0.653 | 0.653 |
TP | 166,135 | 198,708 | 252,967 | 171,511 | 193,430 |
FP | 36,526,998 | 28,315,554 | 583,920 | 40,370,908 | 30,878,750 |
TN | 72,145,972 | 86,003,592 | 114,019,375 | 74,232,290 | 83,724,448 |
FN | 84,113 | 65,422 | 11,820 | 93,276 | 71,357 |
Missing data | 5,944,864 | 284,806 | 0 | 97 | 97 |
AUC | 0.728 | 0.819 | – | 0.711 | 0.811 |
Accuracy | 66.39% | 75.23% | 99.48% | 64.77% | 73.06% |
Sensitivity | 66.39% | 75.23% | 95.54% | 64.77% | 73.05% |
Specificity | 66.39% | 75.23% | 99.49% | 64.77% | 73.06% |
PPV | 0.45% | 0.70% | 30.23% | 0.42% | 0.62% |
NPV | 99.88% | 99.92% | 99.99% | 99.87% | 99.91% |