Table 4 Performance of the bioinformatics tools on the alternative acceptor splice sites (n = 103,972)
SVM-BPfinder | BPP | Branchpointer | LaBranchoR | RNABPS | |
|---|---|---|---|---|---|
Cutoff | 0.76997 | 5.55569 | – | 0.66239 | 0.6962 |
TP | 28,990 | 29,953 | 16,671 | 29,346 | 29,320 |
FP | 22,608 | 22,033 | 206 | 22,640 | 21,894 |
TN | 29,132 | 29,953 | 51,780 | 29,346 | 30,092 |
FN | 22,499 | 22,033 | 35,315 | 22,640 | 21,274 |
Missing data | 743 | 0 | 0 | 0 | 1482 |
AUC | 0.595 | 0.591 | – | 0.592 | 0.612 |
Accuracy | 56.3% | 57.6% | 65.8% | 56.4% | 57.9% |
Sensitivity | 56.3% | 57.6% | 32.1% | 56.4% | 57.9% |
Specificity | 56.3% | 57.6% | 99.6% | 56.4% | 57.9% |