Table 2 Osmoregulation-related differentially expressed genes (DEGs) regulated after stressed in group C vs. S, C vs. A and C vs. SA
Groups | Gene name | Pathway ID | Log2 (Fold Change) | P-value |
|---|---|---|---|---|
chloride channel 2(clcn2) | K05011 | −2.57413 | 0.00005 | |
two pore calcium channel protein 3(tpcn3) | K16897 | 1.32543 | 0.00005 | |
transient receptor potential cation channel subfamily V member 4(TRPV4) | K04973 | −1.41868 | 0.00005 | |
aquaporin-1(AQP1) | K09864 | 1.3813 | 0.00005 | |
aquaporin-3(AQP3) | K09876 | −3.17706 | 0.00005 | |
prolactin receptor (prlr) | K05081 | −1.16648 | 0.00005 | |
potassium inwardly-rectifying channel subfamily J member 2(KCNJ2) | K04996 | 2.21687 | 0.00005 | |
calcium/calmodulin-dependent protein kinase (CaM kinase) II (CAMK2) | K04515 | 1.80579 | 0.00005 | |
hyperpolarization activated cyclic nucleotide-gated potassium channel 4(HCN4) | K04957 | −1.28146 | 0.00005 | |
C-VS-S | phospholipid-translocating ATPase (ATP10b) | K01530 | −1.29862 | 0.00005 |
carbonic anhydrase (CA) | K01672 | −1.53219 | 0.00005 | |
carbonic anhydrase 4(CA4) | K18246 | 3.0621 | 0.00105 | |
sodium/potassium/chloride transporter (SLC12A2/ NKCC1) | K10951 | 2.49218 | 0.00005 | |
solute carrier family 9 (sodium/hydrogen exchanger), member 3(SLC9A3) | K12040 | −1.05992 | 0.00205 | |
Na(+)/H(+) exchange regulatory cofactor NHE-RF2(SLC9A3R2/NHERF2) | K13358 | 1.04245 | 0.00005 | |
sodium bicarbonate cotransporter (SLC4A4/NBC1) | K13575 | −1.50471 | 0.00005 | |
mitogen-activated protein kinase 8(mapk4) | K06855 | 1.66571 | 0.00005 | |
mitogen-activated protein kinase 8 interacting protein 3 | K04436 | 1.67422 | 0.0065 | |
regulator of G-protein signaling (RGS) | K16449 | −3.14363 | 0.00005 | |
Solute carrier family 9 (sodium/hydrogen exchanger), member 5(NHE5) | K14723 | 4.08758 | 0.00005 | |
Chloride channel 2(CLCN2) | K05011 | 1.36324 | 0.00005 | |
Aquaporin-3(AQP3) | K09876 | −1.57718 | 0.00005 | |
Aquaporin-1(AQP1) | K09864 | 1.27087 | 0.00005 | |
Carbonic anhydrase 4(CA4) | K18246 | 2.33457 | 0.00005 | |
Transient receptor potential cation channel subfamily V member 6(trpv6) | K04975 | 2.87291 | 0.00005 | |
Chloride channel 3/4/5(CLCN5) | K05012 | −1.23945 | 0.00005 | |
Two pore calcium channel protein 3(TPCN3) | 0.00005 | 1.12829 | 0.00005 | |
Potassium inwardly-rectifying channel subfamily J member 2(KCNJ2) | K04996 | 1.73207 | 0.00005 | |
Hyperpolarization activated cyclic nucleotide-gated potassium channel 4(HCN4) | K04957 | −1.18463 | 0.00005 | |
Potassium channel subfamily K member 5(KCNK5) | K04916 | 1.31934 | 0.00005 | |
C-VS-A | Calcium/calmodulin-dependent protein kinase (cam kinase) II (CAMK2) | K04515 | −1.1669 | 0.004 |
Phospholipid-translocating atpase (ATP10b) | K01530 | −1.11012 | 0.00005 | |
Phospholipid-translocating atpase (ATP8b4) | K01530 | 1.25176 | 0.00005 | |
Sodium/potassium-transporting atpase subunit alpha (ATP1A) | K01539 | −1.98927 | 0.00005 | |
Solute carrier family 8 (sodium/calcium exchanger)(SLC8A1) | K05849 | 3.17412 | 0.00005 | |
Solute carrier family 4 (anion exchanger), member 2(SLC4A2) | K13855 | −2.43824 | 0.00005 | |
Sodium bicarbonate cotransporter (SLC4A4/NBC1) | K13575 | 1.30546 | 0.00005 | |
Sodium/potassium/chloride transporterslc12a2/NKCC1) | K10951 | 1.05921 | 0.00005 | |
MFS transporter, SP family, solute carrier family 2 member 8(SLC2A8) | K08145 | 1.82715 | 0.01315 | |
Mitogen-activated protein kinase6(MAPK6) | K06855 | 1.12481 | 0.00005 | |
Mitogen-activated protein kinase4 kinase 4(MAPK4k4) | K04407 | −1.96545 | 0.00005 | |
Mitogen-activated protein kinase 8 interacting protein 3 | K04436 | 1.0482 | 0.00025 | |
Regulator of G-protein signaling (rgs12) | K16449 | 1.23556 | 0.01035 | |
Carbonic anhydrase (CA) | K01672 | −1.63577 | 0.00005 | |
Carbonic anhydrase 4(CA4) | K18246 | 2.00696 | 0.00005 | |
Potassium channel subfamily K member 5(kcnk5) | K04916 | 1.86814 | 0.00005 | |
Transient receptor potential cation channel subfamily V member 6(TRPV6) | K04975 | 4.23057 | 0.00005 | |
Calcium/calmodulin-dependent protein kinase (cam kinase) II (CAMK2) | K04515 | 1.29023 | 0.00005 | |
Chloride channel 3/4/5(CLCN5) | K05012 | 1.20394 | 0.00005 | |
Hyperpolarization activated cyclic nucleotide-gated potassium channel 4(HCN4) | K04957 | −1.36233 | 0.00005 | |
C-VS-SA | Phospholipid-translocating atpase (ATP10b) | K01530 | −2.14108 | 0.0008 |
Aquaporin-9(AQP9) | K09877 | 2.47715 | 0.0046 | |
Aquaporin-3(AQP3) | K09876 | −2.15244 | 0.00005 | |
Adenylate cyclase 3(ADCY3) | K08043 | 1.52349 | 0.0108 | |
Sodium/potassium/chloride transporter (SLC12A2/NKCC1) | K10951 | 1.21719 | 0.00005 | |
Sodium bicarbonate cotransporter (SLC4A4/NBC1) | K13575 | 1.23287 | 0.00005 | |
Solute carrier family 8 (sodium/calcium exchanger)(SLC8A1) | K05849 | 4.74133 | 0.00005 | |
Mitogen-activated protein kinase4(MAPK4) | K06855 | 1.36517 | 0.00005 | |
Mitogen-activated protein kinase4 kinase 4(MAPKk4) | K04407 | 1.43318 | 0.0017 | |
Regulator of G-protein signaling (RGS) | K16449 | −1.93502 | 0.00005 |