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Fig. 3 | BMC Genomics

Fig. 3

From: Transcriptome analyses of liver in newly-hatched chicks during the metabolic perturbation of fasting and re-feeding reveals THRSPA as the key lipogenic transcription factor

Fig. 3

Stacked-bar graph of seven pairwise treatment contrasts showing the highest numbers of up-regulated and down-regulated “Analysis Ready” (AR)-DEGs among the 45 possible pairwise contrasts of 10 treatment conditions (Panel a). The Venn diagrams provide the numbers of unique and commonly shared AR-DEGs found within the meaningful contrasts. The Venn diagram in Panel b compared three contrasts of AR-DEGs in chicks that were either fasted for 4 h immediately after hatching (D0FAST4h), fasted for 24 h (D1FAST24h) or fasted for 48 h (D2FAST48h) versus chicks that were either fully-fed for 24 h (D1FED24h) or 48 h (D2FED48h). Likewise, the recovery from prolonged fasting (D2FAST48h) was examined by three refeeding contrasts (D2REFED4h, D3REFED24h or D4REFED48h) (Panel c). The number of AR-DEGs found in each contrast is shown in brackets, while numbers within arcs represents genes shared between or among contrasts. Annotated lists of AR-DEGs found in the five contrasts are provided by multiple worksheets in Additional file 3

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