Fig. 8

Distribution of a pairwise dN/dS ratios, b synonymous substitution rates, and c nonsynonymous substitution rates of orthologous transcripts. Dashed red lines denote 95 percentiles based on distribution of nontoxins. Lines beneath plots indicate toxins, and toxins with values greater than the 95 percentile are marked with blue arrows. In c, toxins above the 95th percentile with elevated synonymous mutation rates (i.e., above the 95th percentile in b are colored yellow. Toxins had statistically higher dN/dS ratios and nonsynonymous substitution rates based on a Wilcoxon signed rank test. Toxin and nontoxin synonymous mutation rates were not significantly different